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Herpesvirus Saimiri Transforms Human T-Cell Clones to Stable Growth without Inducing Resistance to Apoptosis

Herpesvirus saimiri (HVS) transforms human T cells to stable growth in vitro. Since HVS codes for two different antiapoptotic proteins, growth transformation by HVS might be expected to confer resistance to apoptosis. We found that the expression of both viral antiapoptotic genes was restricted to c...

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Autori principali: Kraft, Michael S., Henning, Golo, Fickenscher, Helmut, Lengenfelder, Doris, Tschopp, Jürg, Fleckenstein, Bernhard, Meinl, Edgar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109767/
https://ncbi.nlm.nih.gov/pubmed/9525639
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