Cellular Proteins Required for Adeno-Associated Virus DNA Replication in the Absence of Adenovirus Coinfection

We previously reported the development of an in vitro adeno-associated virus (AAV) DNA replication system. The system required one of the p5 Rep proteins encoded by AAV (either Rep78 or Rep68) and a crude adenovirus (Ad)-infected HeLa cell cytoplasmic extract to catalyze origin of replication-depend...

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Main Authors: Ni, Tie-Hua, McDonald, William F., Zolotukhin, Irene, Melendy, Thomas, Waga, Shou, Stillman, Bruce, Muzyczka, Nicholas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC109722/
https://ncbi.nlm.nih.gov/pubmed/9525597
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