A Replication-Competent Retrovirus Arising from a Split-Function Packaging Cell Line Was Generated by Recombination Events between the Vector, One of the Packaging Constructs, and Endogenous Retroviral Sequences

Previously we reported the presence of a replication-competent retrovirus in supernatant from a vector-producing line derived from a widely used split-function amphotropic packaging cell line. Rigorous routine screening of all retroviral stocks produced in our laboratory has not, previously or since...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chong, Heung, Starkey, William, Vile, Richard G.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 1998
الموضوعات:
Gene Therapy
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC109708/
https://ncbi.nlm.nih.gov/pubmed/9525583
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة