Cryoelectron Microscopic Examination of Human Immunodeficiency Virus Type 1 Virions with Mutations in the Cyclophilin A Binding Loop

The human immunodeficiency virus type 1 capsid protein contains a conserved P(217)X(4)PX(2)PX(5)P(231) motif. Mutation at Pro-222 decreases virion incorporation of cyclophilin A, while mutation at Pro-231 abolishes infectivity. Although viral RNA incorporation and protease cleavage of the Gag precur...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Kong, Lawrence B., An, DongSung, Ackerson, Bradley, Canon, Jude, Rey, Osvaldo, Chen, Irvin S. Y., Krogstad, Paul, Stewart, Phoebe L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Animal Viruses
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109671/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.4403-4407.1998
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