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Chromosome Structure and Human Immunodeficiency Virus Type 1 cDNA Integration: Centromeric Alphoid Repeats Are a Disfavored Target

Integration of retroviral cDNA into host chromosomal DNA is an essential and distinctive step in viral replication. Despite considerable study, the host determinants of sites for integration have not been fully clarified. To investigate integration site selection in vivo, we used two approaches. (i)...

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Udgivet i:J Virol
Principais autores: Carteau, Sandrine, Hoffmann, Christopher, Bushman, Frederic
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.4005-4014.1998
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