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Transgenic Mice Secreting Coronavirus Neutralizing Antibodies into the Milk

Ten lines of transgenic mice secreting transmissible gastroenteritis coronavirus (TGEV) neutralizing recombinant monoclonal antibodies (rMAbs) into the milk were generated. The rMAb light- and heavy-chain genes were assembled by fusing the genes encoding the variable modules of the murine MAb 6A.C3,...

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Bibliographic Details
Main Authors: Sola, Isabel, Castilla, Joaquín, Pintado, Belén, Sánchez-Morgado, José M., Whitelaw, C. Bruce A., Clark, A. John, Enjuanes, Luis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109598/
https://ncbi.nlm.nih.gov/pubmed/9557658
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