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N-Terminal Protease of Pestiviruses: Identification of Putative Catalytic Residues by Site-Directed Mutagenesis

Pestiviruses are the only members of the Flaviviridae that encode a nonstructural protease at the N terminus of their polyproteins. This N-terminal protease (N(pro)) cleaves itself off of the nascent polyprotein autocatalytically and thereby generates the N terminus of the adjacent viral capsid prot...

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Auteurs principaux: Rümenapf, Tillmann, Stark, Robert, Heimann, Manuela, Thiel, Heinz-Jürgen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109561/
https://ncbi.nlm.nih.gov/pubmed/9499122
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