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N-Terminal Protease of Pestiviruses: Identification of Putative Catalytic Residues by Site-Directed Mutagenesis

Pestiviruses are the only members of the Flaviviridae that encode a nonstructural protease at the N terminus of their polyproteins. This N-terminal protease (N(pro)) cleaves itself off of the nascent polyprotein autocatalytically and thereby generates the N terminus of the adjacent viral capsid prot...

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Udgivet i:J Virol
Principais autores: Rümenapf, Tillmann, Stark, Robert, Heimann, Manuela, Thiel, Heinz-Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9499122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.3.2544-2547.1998
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