Extended Minus-Strand DNA as Template for R-U5-Mediated Second-Strand Transfer in Recombinational Rescue of Primer Binding Site-Modified Retroviral Vectors

We have previously demonstrated recombinational rescue of primer binding site (PBS)-impaired Akv murine leukemia virus-based vectors involving initial priming on endogenous viral sequences and template switching during cDNA synthesis to obtain PBS complementarity in second-strand transfer of reverse...

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Main Authors: Mikkelsen, Jacob Giehm, Lund, Anders H., Dybkær, Karen, Duch, Mogens, Pedersen, Finn Skou
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1998
Ábhair:
Animal Viruses
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109556/
https://ncbi.nlm.nih.gov/pubmed/9499117
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