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A Putative α-Helical Structure Which Overlaps the Capsid-p2 Boundary in the Human Immunodeficiency Virus Type 1 Gag Precursor Is Crucial for Viral Particle Assembly

The capsid (CA) and nucleocapsid domains of the human immunodeficiency virus type 1 Gag polyprotein are separated by the p2 spacer peptide, which is essential for virus replication. Previous studies have revealed that p2 has an important role in virus morphogenesis. In this paper, we show that a cru...

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Main Authors: Accola, Molly A., Höglund, Stefan, Göttlinger, Heinrich G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC109501/
https://ncbi.nlm.nih.gov/pubmed/9499062
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