Preemptive CD8 T-Cell Immunotherapy of Acute Cytomegalovirus Infection Prevents Lethal Disease, Limits the Burden of Latent Viral Genomes, and Reduces the Risk of Virus Recurrence

In the immunocompetent host, primary cytomegalovirus (CMV) infection is resolved by the immune response without causing overt disease. The viral genome, however, is not cleared but is maintained in a latent state that entails a risk of virus recurrence and consequent organ disease. By using murine C...

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Pubblicato in:	J Virol
Autori principali:	Steffens, Hans-Peter, Kurz, Sabine, Holtappels, Rafaela, Reddehase, Matthias J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Viral Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9499030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.3.1797-1804.1998
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