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Inhibition of Human Cytomegalovirus DNA Maturation by a Benzimidazole Ribonucleoside Is Mediated through the UL89 Gene Product

2-Bromo-5,6-dichloro-1-β-d-ribofuranosyl benzimidazole (BDCRB) is a member of a new class of benzimidazole ribonucleosides which inhibit human cytomegalovirus (HCMV) late in the replication cycle without inhibiting viral DNA synthesis. We show here that polygenomic concatemeric HCMV DNA does not mat...

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Pubblicato in:J Virol
Autori principali: Underwood, Mark R., Harvey, Robert J., Stanat, Sylvia C., Hemphill, Mary Lou, Miller, Teresa, Drach, John C., Townsend, Leroy B., Biron, Karen K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.717-725.1998
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