Human Herpesvirus 8 Encodes an Interferon Regulatory Factor (IRF) Homolog That Represses IRF-1-Mediated Transcription

Human herpesvirus 8 (HHV-8) is the probable viral etiologic agent for Kaposi’s sarcoma. The HHV-8 genome encodes viral interferon regulatory factor (vIRF), a gene product that has homology to the IRF family of transcription factors. We demonstrate that vIRF inhibits responses to type I and type II i...

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Pubblicato in:	J Virol
Autori principali:	Zimring, James C., Goodbourn, Stephen, Offermann, Margaret K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Viral Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109425/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.701-707.1998
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