Stimulation of Cyclin-Dependent Kinase Activity and G(1)- to S-Phase Transition in Human Lymphocytes by the Human T-Cell Leukemia/Lymphotropic Virus Type 1 Tax Protein

The human T-cell leukemia/lymphotropic virus type 1 (HTLV-1) induces a malignant lymphocytic disease. The HTLV-1 transactivator protein, Tax, is believed to be crucial for the development of the disease since it is transforming in vitro and induces tumors in transgenic animals. Although the transcri...

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Bibliographic Details
Main Authors: Schmitt, Iris, Rosin, Oliver, Rohwer, Peter, Gossen, Manfred, Grassmann, Ralph
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109417/
https://ncbi.nlm.nih.gov/pubmed/9420268
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