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Saccharomyces cerevisiae Msh2p and Msh6p ATPase Activities Are Both Required during Mismatch Repair

In the Saccharomyces cerevisiae Msh2p-Msh6p complex, mutations that were predicted to disrupt ATP binding, ATP hydrolysis, or both activities in each subunit were created. Mutations in either subunit resulted in a mismatch repair defect, and overexpression of either mutant subunit in a wild-type str...

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Bibliographic Details
Main Authors: Studamire, Barbara, Quach, Tony, Alani, Eric
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109340/
https://ncbi.nlm.nih.gov/pubmed/9819445
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