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Exploring Functional Redundancy in the Immunoglobulin μ Heavy-Chain Gene Enhancer

Immunoglobulin (Ig) μ heavy-chain gene enhancer activity is mediated by multiple DNA binding proteins. Mutations of several protein binding sites in the enhancer do not affect enhancer activity significantly. This feature, termed redundancy, is thought to be due to functional compensation of the mut...

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Udgivet i:Mol Cell Biol
Principais autores: Dang, Wei, Nikolajczyk, Barbara S., Sen, Ranjan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6870
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