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Characterization of Novel Parent-Specific Epigenetic Modifications Upstream of the Imprinted Mouse H19 Gene

Genomic imprinting results in parent-specific monoallelic expression of a small number of genes in mammals. The identity of imprints is unknown, but much evidence points to a role for DNA methylation. The maternal alleles of the imprinted H19 gene are active and hypomethylated; the paternal alleles...

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Autors principals: Szabó, Piroska E., Pfeifer, Gerd P., Mann, Jeffrey R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109260/
https://ncbi.nlm.nih.gov/pubmed/9774690
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