Glucocorticoid Receptor, C/EBP, HNF3, and Protein Kinase A Coordinately Activate the Glucocorticoid Response Unit of the Carbamoylphosphate Synthetase I Gene

A single far-upstream enhancer is sufficient to confer hepatocyte-specific, glucocorticoid- and cyclic AMP-inducible periportal expression to the carbamoylphosphate synthetase I (CPS) gene. To identify the mechanism of hormone-dependent activation, the composition and function of the enhancer have b...

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Main Authors: Christoffels, Vincent M., Grange, Thierry, Kaestner, Klaus H., Cole, Timothy J., Darlington, Gretchen J., Croniger, Colleen M., Lamers, Wouter H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1998
Ábhair:
Transcriptional Regulation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109217/
https://ncbi.nlm.nih.gov/pubmed/9774647
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