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Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution
In humans, there are two isoforms each of clathrin heavy chain (CHC17 and CHC22) and light chain (LCa and LCb) subunits, all encoded by separate genes. CHC17 forms the ubiquitous clathrin-coated vesicles that mediate membrane traffic. CHC22 is implicated in specialized membrane organization in skele...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1091751/ https://ncbi.nlm.nih.gov/pubmed/15883369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502058102 |
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