Discontinuous Subgenomic RNA Synthesis in Arteriviruses Is Guided by an RNA Hairpin Structure Located in the Genomic Leader Region

Nidoviruses produce an extensive 3′-coterminal nested set of subgenomic (sg) mRNAs, which are used to express structural proteins and sometimes accessory proteins. In arteriviruses and coronaviruses, these mRNAs contain a common 5′ leader sequence, derived from the genomic 5′ end. The joining of the...

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Main Authors: van den Born, Erwin, Posthuma, Clara C., Gultyaev, Alexander P., Snijder, Eric J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091703/
https://ncbi.nlm.nih.gov/pubmed/15858015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6312-6324.2005
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