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Biosynthesis and Function of the Modified DNA Base β-d-Glucosyl-Hydroxymethyluracil in Trypanosoma brucei

β-d-Glucosyl-hydroxymethyluracil, also called J, is a modified DNA base conserved among kinetoplastid flagellates. In Trypanosoma brucei, the majority of J is present in repetitive DNA but the partial replacement of thymine by J also correlates with transcriptional repression of the variant surface...

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Udgivet i:Mol Cell Biol
Principais autores: van Leeuwen, Fred, Kieft, Rudo, Cross, Mike, Borst, Piet
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109150/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5643
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