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CUS2, a Yeast Homolog of Human Tat-SF1, Rescues Function of Misfolded U2 through an Unusual RNA Recognition Motif

A screen for suppressors of a U2 snRNA mutation identified CUS2, an atypical member of the RNA recognition motif (RRM) family of RNA binding proteins. CUS2 protein is associated with U2 RNA in splicing extracts and interacts with PRP11, a subunit of the conserved splicing factor SF3a. Absence of CUS...

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Détails bibliographiques
Auteurs principaux: Yan, Dong, Perriman, Rhonda, Igel, Haller, Howe, Kenneth J., Neville, Megan, Ares, Manuel
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109085/
https://ncbi.nlm.nih.gov/pubmed/9710584
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