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CDC42 and FGD1 Cause Distinct Signaling and Transforming Activities

Activated forms of different Rho family members (CDC42, Rac1, RhoA, RhoB, and RhoG) have been shown to transform NIH 3T3 cells as well as contribute to Ras transformation. Rho family guanine nucleotide exchange factors (GEFs) (also known as Dbl family proteins) that activate CDC42, Rac1, and RhoA al...

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Détails bibliographiques
Auteurs principaux: Whitehead, Ian P., Abe, Karon, Gorski, Jerome L., Der, Channing J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109055/
https://ncbi.nlm.nih.gov/pubmed/9671479
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