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Sequence-Directed Base Mispairing in Human Oncogenes

The most frequently observed mutations in ras oncogenes in solid human tumors are GC→AT transitions at the 3′ G residue of the GG doublet in codon 12 of these oncogenes. We had shown previously that mutagenesis by thymidine occurred with the same sequence specificity in mammalian cells, in that muta...

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Publicat a:Mol Cell Biol
Autors principals: Lall, Lavanya, Davidson, Richard L.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.8.4659
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