Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway

Interleukin 10 (IL-10) is a pleiotropic cytokine with well known antiinflammatory, immunosuppressive, and immunostimulatory properties. Chronic allograft rejection, characterized by vascular neointimal proliferation, is a major cause of organ transplant loss, particularly in heart and kidney transpl...

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Hauptverfasser: Chen, Sifeng, Kapturczak, Matthias H., Wasserfall, Clive, Glushakova, Olena Y., Campbell-Thompson, Martha, Deshane, Jessy S., Joseph, Reny, Cruz, Pedro E., Hauswirth, William W., Madsen, Kirsten M., Croker, Byron P., Berns, Kenneth I., Atkinson, Mark A., Flotte, Terence R., Tisher, C. Craig, Agarwal, Anupam
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1090475/
https://ncbi.nlm.nih.gov/pubmed/15878989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502407102
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