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Rapamycin Induces the G(0) Program of Transcriptional Repression in Yeast by Interfering with the TOR Signaling Pathway

The macrolide antibiotic rapamycin inhibits cellular proliferation by interfering with the highly conserved TOR (for target of rapamycin) signaling pathway. Growth arrest of budding yeast cells treated with rapamycin is followed by the program of molecular events that characterizes entry into G(0) (...

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Detalhes bibliográficos
Main Authors: Zaragoza, Dean, Ghavidel, Ataollah, Heitman, Joseph, Schultz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109032/
https://ncbi.nlm.nih.gov/pubmed/9671456
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