Gab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase

Gab1 has structural similarities with Drosophila DOS (daughter of sevenless), which is a substrate of the protein tyrosine phosphatase Corkscrew. Both Gab1 and DOS have a pleckstrin homology domain and tyrosine residues, potential binding sites for various SH2 domain-containing adapter molecules whe...

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Detalhes bibliográficos
Main Authors: Takahashi-Tezuka, Mariko, Yoshida, Yuichi, Fukada, Toshiyuki, Ohtani, Takuya, Yamanaka, Yojiro, Nishida, Keigo, Nakajima, Koichi, Hibi, Masahiko, Hirano, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108995/
https://ncbi.nlm.nih.gov/pubmed/9632795
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