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The Mdm2 Oncoprotein Interacts with the Cell Fate Regulator Numb

The Mdm2 oncoprotein is a well-known inhibitor of the p53 tumor suppressor, but it may also possess p53-independent activities. In search of such p53-independent activities, the yeast two-hybrid screen was employed to identify Mdm2-binding proteins. We report that in vitro and in transfected cells,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Juven-Gershon, Tamar, Shifman, Ohad, Unger, Tamar, Elkeles, Adi, Haupt, Ygal, Oren, Moshe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108982/
https://ncbi.nlm.nih.gov/pubmed/9632782
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