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Requirement for Activation of the Serine-Threonine Kinase Akt (Protein Kinase B) in Insulin Stimulation of Protein Synthesis but Not of Glucose Transport

A wide variety of biological activities including the major metabolic actions of insulin is regulated by phosphatidylinositol (PI) 3-kinase. However, the downstream effectors of the various signaling pathways that emanate from PI 3-kinase remain unclear. Akt (protein kinase B), a serine-threonine ki...

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Udgivet i:Mol Cell Biol
Principais autores: Kitamura, Tadahiro, Ogawa, Wataru, Sakaue, Hiroshi, Hino, Yasuhisa, Kuroda, Shoji, Takata, Masafumi, Matsumoto, Michihiro, Maeda, Tetsuo, Konishi, Hiroaki, Kikkawa, Ushio, Kasuga, Masato
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.3708
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