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Optimal Activation of an Endogenous Gene by HOX11 Requires the NH(2)-Terminal 50 Amino Acids
The HOX11 homeobox gene was first identified through studies of the t(7;10) and t(10;14) chromosomal translocations of acute T-cell leukemia. In addition, analysis of Hox11(−/−) mice has demonstrated a critical role for this gene in murine spleen development. A possible mode of in vivo function for...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC108931/ https://ncbi.nlm.nih.gov/pubmed/9584190 |
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