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A Gene-Targeting Approach Identifies a Function for the First Intron in Expression of the α1(I) Collagen Gene

The role of the first intron of the Col1A1 gene in the regulation of type I collagen synthesis remains uncertain and controversial despite numerous studies that have made use of transgenic and transfection experiments. To examine the importance of the first intron in regulation of the gene, we have...

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Autores principales: Hormuzdi, Sheriar G., Penttinen, Risto, Jaenisch, Rudolf, Bornstein, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC108918/
https://ncbi.nlm.nih.gov/pubmed/9584177
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