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Cooperation among Multiple Transcription Factors Is Required for Access to Minimal T-Cell Receptor α-Enhancer Chromatin In Vivo

To understand the molecular basis for the dramatic functional synergy between transcription factors that bind to the minimal T-cell receptor α enhancer (Eα), we analyzed enhancer occupancy in thymocytes of transgenic mice in vivo by genomic footprinting. We found that the formation of a multiprotein...

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Pubblicato in:Mol Cell Biol
Autori principali: Hernandez-Munain, Cristina, Roberts, Joseph L., Krangel, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108904/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9584163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.6.3223
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