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Inhibition of Cyclin D1 Kinase Activity Is Associated with E2F-Mediated Inhibition of Cyclin D1 Promoter Activity through E2F and Sp1

Coordinated interactions between cyclin-dependent kinases (Cdks), their target “pocket proteins” (the retinoblastoma protein [pRB], p107, and p130), the pocket protein binding E2F-DP complexes, and the Cdk inhibitors regulate orderly cell cycle progression. The cyclin D1 gene encodes a regulatory su...

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Hlavní autoři: Watanabe, Genichi, Albanese, Chris, Lee, Richard J., Reutens, Anne, Vairo, Gino, Henglein, Berthold, Pestell, Richard G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC108903/
https://ncbi.nlm.nih.gov/pubmed/9584162
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