5′ Processing of tRNA Precursors Can Be Modulated by the Human La Antigen Phosphoprotein

Eukaryotic precursor (pre)-tRNAs are processed at both ends prior to maturation. Pre-tRNAs and other nascent transcripts synthesized by RNA polymerase III are bound at their 3′ ends at the sequence motif UUU(OH) [3′ oligo(U)] by the La antigen, a conserved phosphoprotein whose role in RNA processing...

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Main Authors: Fan, Hao, Goodier, John L., Chamberlain, Joel R., Engelke, David R., Maraia, Richard J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
主題:
Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC108902/
https://ncbi.nlm.nih.gov/pubmed/9584161
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