Role of the Negative Charges in the Cytosolic Domain of TOM22 in the Import of Precursor Proteins into Mitochondria

TOM22 is an essential mitochondrial outer membrane protein required for the import of precursor proteins into the organelles. The amino-terminal 84 amino acids of TOM22 extend into the cytosol and include 19 negatively and 6 positively charged residues. This region of the protein is thought to inter...

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Bibliographic Details
Main Authors: Nargang, Frank E., Rapaport, Doron, Ritzel, R. Gary, Neupert, Walter, Lill, Roland
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Cell and Organelle Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108899/
https://ncbi.nlm.nih.gov/pubmed/9584158
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