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Interaction between directional epistasis and average mutational effects.
We investigate the relationship between the average fitness decay due to single mutations and the strength of epistatic interactions in genetic sequences. We observe that epistatic interactions between mutations are correlated to the average fitness decay, both in RNA secondary structure prediction...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088765/ https://ncbi.nlm.nih.gov/pubmed/11454290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2001.1690 |
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