Repression of GCN5 Histone Acetyltransferase Activity via Bromodomain-Mediated Binding and Phosphorylation by the Ku–DNA-Dependent Protein Kinase Complex

GCN5, a putative transcriptional adapter in humans and yeast, possesses histone acetyltransferase (HAT) activity which has been linked to GCN5’s role in transcriptional activation in yeast. In this report, we demonstrate a functional interaction between human GCN5 (hGCN5) and the DNA-dependent prote...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Barlev, Nickolai A., Poltoratsky, Vladimir, Owen-Hughes, Tom, Ying, Carol, Liu, Lin, Workman, Jerry L., Berger, Shelley L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1349
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