Repression of GCN5 Histone Acetyltransferase Activity via Bromodomain-Mediated Binding and Phosphorylation by the Ku–DNA-Dependent Protein Kinase Complex

GCN5, a putative transcriptional adapter in humans and yeast, possesses histone acetyltransferase (HAT) activity which has been linked to GCN5’s role in transcriptional activation in yeast. In this report, we demonstrate a functional interaction between human GCN5 (hGCN5) and the DNA-dependent prote...

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Detalhes bibliográficos
Main Authors: Barlev, Nickolai A., Poltoratsky, Vladimir, Owen-Hughes, Tom, Ying, Carol, Liu, Lin, Workman, Jerry L., Berger, Shelley L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108848/
https://ncbi.nlm.nih.gov/pubmed/9488450
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