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Mechanisms of tolerance induction: blockade of co-stimulation.
Induction of tolerance to transplantation antigens is believed to be a promising way to achieve long-term allograft survival without a deleterious immunosuppressive regimen. T-cell activation, which is an essential feature of graft rejection, requires a first signal provided by T-cell receptor (TCR)...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088452/ https://ncbi.nlm.nih.gov/pubmed/11375068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2001.0842 |
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