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Mechanisms of tolerance induction: blockade of co-stimulation.

Induction of tolerance to transplantation antigens is believed to be a promising way to achieve long-term allograft survival without a deleterious immunosuppressive regimen. T-cell activation, which is an essential feature of graft rejection, requires a first signal provided by T-cell receptor (TCR)...

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Detalhes bibliográficos
Main Authors: Sebille, F, Vanhove, B, Soulillou, J P
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088452/
https://ncbi.nlm.nih.gov/pubmed/11375068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2001.0842
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