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Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells

Dendritic cells (DCs) have the capacity to prime tumor-specific T cell responses and are considered as potentially effective vaccines for immunotherapy of cancer. Critical parameters in the development of DC vaccines are the source of tumor antigen (TA) and the mode of DC-loading. Whole tumor cells...

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Autors principals: Groh, Veronika, Li, Yongqing Q., Cioca, Daniel, Hunder, Naomi N., Wang, Wei, Riddell, Stanley R., Yee, Cassian, Spies, Thomas
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088382/
https://ncbi.nlm.nih.gov/pubmed/15824323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501953102
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