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Invading the Yeast Nucleus: a Nuclear Localization Signal at the C Terminus of Ty1 Integrase Is Required for Transposition In Vivo

Retrotransposon Ty1 faces a formidable cell barrier during transposition—the yeast nuclear membrane which remains intact throughout the cell cycle. We investigated the mechanism by which transposition intermediates are transported from the cytoplasm (the presumed site of Ty1 DNA synthesis) to the nu...

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Autori principali: Kenna, Margaret A., Brachmann, Carrie Baker, Devine, Scott E., Boeke, Jef D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC108824/
https://ncbi.nlm.nih.gov/pubmed/9448009
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