A Novel, Multifunctional c-Cbl Binding Protein in Insulin Receptor Signaling in 3T3-L1 Adipocytes

The protein product of the c-Cbl proto-oncogene is prominently tyrosine phosphorylated in response to insulin in 3T3-L1 adipocytes and not in 3T3-L1 fibroblasts. After insulin-dependent tyrosine phosphorylation, c-Cbl specifically associates with endogenous c-Crk and Fyn. These results suggest a rol...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ribon, Vered, Printen, John A., Hoffman, Noah G., Kay, Brian K., Saltiel, Alan R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9447983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.2.872
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