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Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites

To investigate retroviral integration targeting on a nucleotide scale, we examined the base frequencies directly surrounding cloned in vivo HIV-1, murine leukemia virus, and avian sarcoma/leukosis virus integrations. Base preferences of up to 2-fold the expected frequencies were found for three viru...

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Библиографические подробности
Главные авторы: Holman, Alexander G., Coffin, John M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087937/
https://ncbi.nlm.nih.gov/pubmed/15802467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501646102
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