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Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors

SMRT (silencing mediator of retinoid acid and thyroid hormone receptor) and NCoR (nuclear receptor corepressor) are transcriptional corepressors that play an essential role in the regulation of development and metabolism. This role is achieved, in part, through the recruitment of a key histone deace...

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Autors principals: Codina, Anna, Love, James D., Li, Yun, Lazar, Mitchell A., Neuhaus, David, Schwabe, John W. R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087922/
https://ncbi.nlm.nih.gov/pubmed/15837933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500299102
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