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Structural basis for the interaction of Asf1 with histone H3 and its functional implications
Asf1 is a conserved histone chaperone implicated in nucleosome assembly, transcriptional silencing, and the cellular response to DNA damage. We solved the NMR solution structure of the N-terminal functional domain of the human Asf1a isoform, and we identified by NMR chemical shift mapping a surface...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087920/ https://ncbi.nlm.nih.gov/pubmed/15840725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500149102 |
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