Human T-Cell Leukemia Virus Type 1 Tax Requires Direct Access to DNA for Recruitment of CREB Binding Protein to the Viral Promoter

Efficient human T-cell leukemia virus type 1 (HTLV-1) replication and viral gene expression are dependent upon the virally encoded oncoprotein Tax. To activate HTLV-1 transcription, Tax interacts with the cellular DNA binding protein cyclic AMP-responsive element binding protein (CREB) and recruits...

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Bibliographic Details
Main Authors: Lenzmeier, Brian A., Giebler, Holli A., Nyborg, Jennifer K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108783/
https://ncbi.nlm.nih.gov/pubmed/9447968
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