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Pairwise Knockdowns of cdc2-Related Kinases (CRKs) in Trypanosoma brucei Identified the CRKs for G(1)/S and G(2)/M Transitions and Demonstrated Distinctive Cytokinetic Regulations between Two Developmental Stages of the Organism
Expression of the cdc2-related kinase 3 (CRK3) together with expression of CRK1, -2, -4, or -6, were knocked down in pairs in the procyclic and bloodstream forms of Trypanosoma brucei, using the RNA interference technique. Double knockdowns of CRK3 and CRK2, CRK4, or CRK6 exerted significant growth...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087811/ https://ncbi.nlm.nih.gov/pubmed/15821135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.4.755-764.2005 |
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