ABCA5 Resides in Lysosomes, and ABCA5 Knockout Mice Develop Lysosomal Disease-Like Symptoms

ABCA5 is a member of the ABC transporter A subfamily, and a mouse orthologue (mABCA5) in newborn mouse brain and neural cells was identified by reverse transcription-PCR. Full-length cDNA cloning revealed that mABCA5 consists of 1,642 amino acid residues and that its putative structure is that of a...

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Hlavní autoři: Kubo, Yoshiyuki, Sekiya, Sayaka, Ohigashi, Megumi, Takenaka, Chiemi, Tamura, Kyoko, Nada, Shigeyuki, Nishi, Tsuyoshi, Yamamoto, Akitsugu, Yamaguchi, Akihito
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087723/
https://ncbi.nlm.nih.gov/pubmed/15870284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.4138-4149.2005
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