The 2μm Plasmid Causes Cell Death in Saccharomyces cerevisiae with a Mutation in Ulp1 Protease

The 2μm circle plasmid confers no phenotype in wild-type Saccharomyces cerevisiae but in a nib1 mutant, an elevated plasmid copy number is associated with cell death. Complementation was used to identify nib1 as a mutant allele of the ULP1 gene that encodes a protease required for removal of a ubiqu...

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Hlavní autoři: Dobson, Melanie J., Pickett, Andrew J., Velmurugan, Soundarapandian, Pinder, Jordan B., Barrett, Lori A., Jayaram, Makkuni, Chew, Joyce S. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Chromosome Structure and Dynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087720/
https://ncbi.nlm.nih.gov/pubmed/15870298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.4299-4310.2005
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