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Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40.
DT40 is an avian leucosis virus-transformed chicken B-lymphocyte line which exhibits high ratios of targeted to random integration of transfected DNA constructs. This efficient targeted integration may be related to the ongoing diversification of the variable segment of the immunoglobulin gene throu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087698/ https://ncbi.nlm.nih.gov/pubmed/11205323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0755 |
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