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Measurement of Intracellular Didanosine and Tenofovir Phosphorylated Metabolites and Possible Interaction of the Two Drugs in Human Immunodeficiency Virus-Infected Patients

Recent work has demonstrated the existence of a systemic interaction between didanosine (ddI) and tenofovir disoproxyl fumarate (TDF) that leads to a significant increase in plasma ddI levels when coadministered with TDF (40 to 50% increase). These two drugs are, respectively, nucleoside and nucleot...

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Detalhes bibliográficos
Main Authors: Pruvost, Alain, Negredo, Eugènia, Benech, Henri, Theodoro, Frédéric, Puig, Jordi, Grau, Eulàlia, García, Elisabet, Moltó, José, Grassi, Jacques, Clotet, Bonaventura
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087635/
https://ncbi.nlm.nih.gov/pubmed/15855513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1907-1914.2005
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