Differential Effects of Prior Exposure to Environmental Mycobacteria on Vaccination with Mycobacterium bovis BCG or a Recombinant BCG Strain Expressing RD1 Antigens

In silico analysis reveals that most protective antigens expressed by the antituberculous vaccine Mycobacterium bovis BCG (BCG) are conserved in M. avium, supporting the hypothesis that exposure to environmental mycobacteria generates cross-reactive immune responses blocking BCG activity. We investi...

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Detalhes bibliográficos
Main Authors: Demangel, Caroline, Garnier, Thierry, Rosenkrands, Ida, Cole, Stewart T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087454/
https://ncbi.nlm.nih.gov/pubmed/15784562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.4.2190-2196.2005
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